人脑损伤后大脑巨噬细胞中MIB-1表达的过程。

The course of MIB-1 expression by cerebral macrophages following human brain injury.

作者信息

Hausmann Roland, Betz Peter

机构信息

Institute of Legal Medicine, Universitätsstrasse 22, D-91054 Erlangen, Germany.

出版信息

Leg Med (Tokyo). 2002 Jun;4(2):79-83. doi: 10.1016/s1344-6223(02)00003-2.

DOI:10.1016/s1344-6223(02)00003-2

PMID:12935673

Abstract

The course of MIB-1 expression by brain macrophages adjacent to cortical contusions has been immunohistochemically investigated during the first 30 weeks after human brain injury, in order to provide data for a forensic wound age estimation. A positive nuclear staining for MIB-1 could be observed earliest after a postinfliction interval of 3 days and regularly in cases with a survival time between 7 and 14 days, whereas in uninjured brain tissue (control group) no cellular MIB-1 reactivity was visible.

摘要

为了提供法医学伤口年龄估计的数据，在人脑损伤后的前30周内，采用免疫组织化学方法研究了皮质挫伤附近脑巨噬细胞的MIB-1表达过程。MIB-1阳性核染色最早可在受伤后3天观察到，在存活时间为7至14天的病例中经常可见，而在未受伤的脑组织（对照组）中未观察到细胞MIB-1反应性。