Khavinson V Kh, Bondarev I E, Butyugov A A
St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of Russian Academy of Medical Sciences.
Bull Exp Biol Med. 2003 Jun;135(6):590-2. doi: 10.1023/a:1025493705728.
Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.
在端粒酶阴性的人胎儿成纤维细胞培养物中添加埃匹塔隆肽可诱导催化亚基的表达、端粒酶的酶活性以及端粒延长，这可能是由于体细胞中端粒酶基因的重新激活，表明延长细胞群体和整个生物体寿命的可能性。
