Jiang Rui, Chen Jiang-Hua, Chen Ming, Li Qi-Meng
Kidney Diseases Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Asian J Androl. 2003 Sep;5(3):251-4.
To study the clinical features of male genital schwannoma.
Five male patients with genital schwannoma admitted from 1991 to 2000 were reviewed. The lesions were located in the prostate, spermatic cord, testis or penis. Tumors were simply resected in 3 patients and radically eradicated in 2.
The average age of the cohort was 37 years. The most common sign at presentation was a palpable genital mass accidentally discovered by the patient or detected by the physician during a physical check. Diagnosis was made through postoperative pathological examination. Follow-up ranged from 2 years to 6 years (mean 4.5 years). Four cases were cured by simple excision and 1 patient with malignant testis schwannoma died of recurrence 1 year after surgery.
Owing to the lack of characteristic clinical manifestation, the final diagnosis relies on postoperative pathological examination. S-100 and vimentin are useful markers for the diagnosis of these tumors.
研究男性生殖器神经鞘瘤的临床特征。
回顾性分析1991年至2000年收治的5例男性生殖器神经鞘瘤患者。病变位于前列腺、精索、睾丸或阴茎。3例患者行肿瘤单纯切除术，2例患者行根治性切除术。
该队列患者的平均年龄为37岁。最常见的表现是患者偶然发现或医生在体格检查时触诊到的生殖器肿物。通过术后病理检查确诊。随访时间为2年至6年（平均4.5年）。4例患者通过单纯切除治愈，1例睾丸恶性神经鞘瘤患者术后1年因复发死亡。
由于缺乏特征性临床表现，最终诊断依赖于术后病理检查。S-100和波形蛋白是诊断这些肿瘤的有用标志物。
