Kobusiak-Prokopowicz Małgorzata, Jołda-Mydłowska Beata, Negrusz-Kawecka Marta
Katedra i Klinika Kardiologii Akademii Medycznej we Wrocławiu.
Przegl Lek. 2003;60(2):85-8.
The aim of the study was to evaluate, if the QT and corrected QT interval dispersion (QTd and QTcd) is a predictor of ventricular arrhythmia during one-year observation in patients with myocardial infarction (MI). Investigations were performed in 36 patients with MI, including 22 men and 14 women, aged 40-84 years. Considered criteria was: sex, MI location, applied/non applied thrombolytic treatment, after which patients were classified into 6 groups. I group--14 women aged 45-84. II group--22 men aged 40-71. III group--22 patients aged 43-68 with inferior wall MI (IMI). IV group--14 patients aged 40-84 with anterior wall MI (AMI). V group--29 patients aged 40-72 with MI treated thrombolytically. VI group--7 patients aged 43-84 with MI, not treated thrombolytically. Control group consisted of 15 healthy persons, aged 27-64. Standard 12-outputs ECG was performed on the 10nd day after admission to the hospital. For further observation ECG is provided within the 6th week, 3rd month, 6th month and 12th month after admission to the hospital were used. Holter monitoring was also performed on the 10nd day and 12th month after admission to the hospital. In patients with MI, independently of its sex, location and treatment, QTd and QTcd was initially increased. In patients treated thrombolytically QTcd was significantly decreasing during following months of observation, what hasn't been observed in patients not treated thrombolytically. There was no correlation between QTd, QTcd and non-sustained ventricular tachycardia in patients with MI.
本研究的目的是评估在心肌梗死（MI）患者的一年观察期内，QT间期和校正QT间期离散度（QTd和QTcd）是否为室性心律失常的预测指标。对36例MI患者进行了研究，其中包括22名男性和14名女性，年龄在40 - 84岁之间。考虑的标准有：性别、MI部位、是否应用溶栓治疗，据此将患者分为6组。I组——14名年龄在45 - 84岁的女性。II组——22名年龄在40 - 71岁的男性。III组——22例年龄在43 - 68岁的下壁心肌梗死（IMI）患者。IV组——14例年龄在40 - 84岁的前壁心肌梗死（AMI）患者。V组——29例年龄在40 - 72岁接受溶栓治疗的MI患者。VI组——7例年龄在43 - 84岁未接受溶栓治疗的MI患者。对照组由15名年龄在27 - 64岁的健康人组成。入院第10天进行标准12导联心电图检查。为进行进一步观察，在入院后第6周、第3个月、第6个月和第12个月进行心电图检查。入院后第10天和第12个月也进行动态心电图监测。在MI患者中，无论其性别、部位和治疗情况如何，QTd和QTcd最初均升高。在接受溶栓治疗的患者中，观察期的后续几个月QTcd显著下降，而在未接受溶栓治疗的患者中未观察到这种情况。MI患者的QTd、QTcd与非持续性室性心动过速之间无相关性。
