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摇头丸所致急性肝衰竭

[Acute liver failure caused by Ecstasy].

作者信息

Ibrányi Endre, Schönléber Julianna

机构信息

Fóvárosi Szent László Kórház, IV. Fertózó Belgyógyászat, Budapest.

出版信息

Orv Hetil. 2003 Jul 20;144(29):1455-6.

PMID:12939867
Abstract

Ecstasy is a synthetic amphetamine widely used as a "week-end" recreational drug because it produces euphoria and eliminate the sense of fatigue. It was initially considered to be a drug with few toxic effects, but later various complications and even fatal cases have been reported. Although the 23 year old woman already tried the Ecstasy in the past, but during the month before the admission she took 8 pills. She became icteric after 6 days taking the last pill and 3 days later her prothrombin level became very low. Due to the rapid deterioration we planed liver transplantation, but since there was no acceptable donor, we could only make plasmapheresis. The autopsy proved sever liver necrosis.

摘要

摇头丸是一种合成苯丙胺类药物,因其能产生欣快感并消除疲劳感而被广泛用作“周末”消遣性毒品。它最初被认为是一种毒性较小的药物,但后来有各种并发症甚至死亡病例的报道。尽管这名23岁的女性过去曾服用过摇头丸,但在入院前一个月她服用了8片。在服用最后一片药6天后她出现黄疸,3天后她的凝血酶原水平变得很低。由于病情迅速恶化,我们计划进行肝移植,但由于没有合适的供体,我们只能进行血浆置换。尸检证实为严重肝坏死。

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