Thacker Naveen, Shendurnikar Niranjan
Deep Children Hospital, Gandhidham, India.
Indian J Pediatr. 2003 Jul;70(7):567-71. doi: 10.1007/BF02723160.
Vaccines against poliomyelitis have been in use for nearly five decades now and have played a major role in progress towards global eradication of the disease. Both the vaccines, (oral polio vaccine and inactivated polio vaccine) and their uses are still debated with particular reference to their selective advantages vs. disadvantages, choice for individual vs. community protection and their administration strategies. Further occurrence of vaccine associated paralytic poliomyelitis with oral vaccine assumes importance in the face of disappearing disease. Further availability of inactivated polio vaccine in India and its various schedules such as sequential and combination schedules show some promise for polio eradication.
脊髓灰质炎疫苗已使用了近五十年,在全球根除该疾病的进程中发挥了重要作用。两种疫苗(口服脊髓灰质炎疫苗和灭活脊髓灰质炎疫苗)及其用途仍存在争议,特别是在它们的选择性优缺点、个体与群体保护的选择以及接种策略方面。面对该疾病的逐渐消失,口服疫苗引发的疫苗相关麻痹型脊髓灰质炎的再次出现具有重要意义。印度灭活脊髓灰质炎疫苗的进一步供应及其各种接种程序,如序贯和联合接种程序,为根除脊髓灰质炎带来了一些希望。