Santiago González de Garibay A M, Castillo Jimeno J M, Villanueva Pérez I, Idígora Planas J, Millán Serrano J A, Puras Gil A M, Sebastián Borruel J L
Servicio de Urología, Hospital Virgen del Camino, Pamplona, Navarra, España.
Arch Esp Urol. 1992 Dec;45(10):985-91.
The results achieved by the use of inert materials via endoscopic injection for the treatment of urological pathologies have been disappointing. Furthermore, these materials are costly, carry the risk of migration and may not be tolerated locally. Autologous fatty tissue, however, is not costly and is tolerated better. The authors have conducted an experiment in the pig to evaluate the degree of resorption and persistence of autologous fat injected into the bladder submucosa. The results show that submucosal injection of autologous fat acts like an autograft and persists as mature fatty tissue. The degree of resorption and/or steatonecrosis is directly related to the amount injected; the smaller the amount used the better the results.
通过内镜注射使用惰性材料治疗泌尿系统疾病所取得的结果令人失望。此外，这些材料成本高昂，存在迁移风险，且可能无法被局部耐受。然而，自体脂肪组织成本不高且耐受性更好。作者在猪身上进行了一项实验，以评估注入膀胱黏膜下层的自体脂肪的吸收程度和持久性。结果表明，黏膜下注射自体脂肪的作用类似于自体移植，并以成熟脂肪组织的形式持续存在。吸收和/或脂肪坏死的程度与注射量直接相关；使用量越小，效果越好。
