Al Otaibi Suad F, Minassian Berge A, Ackerley Cameron A, Logan William J, Weiss Shelly
Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario.
J Child Neurol. 2003 Jul;18(7):499-501. doi: 10.1177/08830738030180070901.
Lafora's disease is a progressive myoclonus epilepsy with onset in adolescence and a gradual decline in cognitive functions and increase in seizure intractability. We present the case of a 16-year-old with precipitous dementia within 6 months of onset. Peripheral biopsies and EPM2A mutation analysis were negative. The diagnosis could be established only by brain biopsy.
