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SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism.

作者信息

Svetel M, Djarmati A, Dragasević N, Savić D, Culjković B, Romac S, Kostić V S

机构信息

Institute of Neurology CCS, School of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

Eur J Neurol. 2003 Sep;10(5):597. doi: 10.1046/j.1468-1331.2003.00671.x.

DOI:10.1046/j.1468-1331.2003.00671.x
PMID:12940846
Abstract

In this study no one of our 85 patients of Serbian origin with young-onset (</= 45 years) dopa-responsive parkinsonism (YOP), previously proved negative for PARK1 and PARK2 mutations, had either spinocerebellar ataxia type 2 (SCA2) or SCA3 mutation. These data do not prove the significance of these two mutations in either sporadic or familial YOP suggestive of Parkinson's disease.

摘要

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