冷冻保存的自体CD34+外周血祖细胞低细胞浓度不会损害移植后的造血恢复。 - Suppr

Low cell concentration of cryopreserved autologous CD34+ peripheral blood progenitor cells does not impair hematopoietic recovery after transplantation.

作者信息

Caravita Tommaso, Bruno Antonio, Adorno Gaspare, Santinelli Susanna, Siniscalchi Agostina, Abruzzese Elisabetta, Palombi Francesca, Tamburini Anna, Ballatore Giovanna, Cudillo Laura, Amadori Sergio, Del Proposto Giampaolo, Isacchi Giancarlo

出版信息

Transfus Apher Sci. 2003 Oct;29(2):189-92. doi: 10.1016/S1473-0502(03)00123-X.

DOI:10.1016/S1473-0502(03)00123-X

PMID:12941360

Abstract

摘要

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Low cell concentration of cryopreserved autologous CD34+ peripheral blood progenitor cells does not impair hematopoietic recovery after transplantation.

Transfus Apher Sci. 2003 Oct;29(2):189-92. doi: 10.1016/S1473-0502(03)00123-X.

Successful cryopreservation of purified autologous CD34+ cells: influence of freezing parameters on cell recovery and engraftment.

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Autologous peripheral blood progenitor cells cryopreserved with 5 and 10 percent dimethyl sulfoxide alone give comparable hematopoietic reconstitution after transplantation.

Transfusion. 2008 May;48(5):877-83. doi: 10.1111/j.1537-2995.2008.01648.x. Epub 2008 Feb 21.

Extensive early apoptosis in frozen-thawed CD34-positive stem cells decreases threshold doses for haematological recovery after autologous peripheral blood progenitor cell transplantation.

Bone Marrow Transplant. 2002 Feb;29(3):249-55. doi: 10.1038/sj.bmt.1703357.

Determining post-thaw CD34+ cell dose of cryopreserved haematopoietic progenitor cells demonstrates high recovery and confirms their integrity.

Vox Sang. 2008 May;94(4):351-7. doi: 10.1111/j.1423-0410.2007.001028.x. Epub 2008 Jan 2.

Peripheral blood and BM CD34+ CD38- cells show better resistance to cryopreservation than CD34+ CD38+ cells in autologous stem cell transplantation.

Cytotherapy. 2004;6(6):571-83. doi: 10.1080/14653240410011918.

Fresh PBSC harvests, but not BM, show temperature-related loss of CD34 viability during storage and transport.

Cytotherapy. 2006;8(2):158-65. doi: 10.1080/14653240600620994.

Conditions for optimal cryopreservation of peripheral stem cells.

Prog Clin Biol Res. 1994;389:649-56.

Controlled-rate versus uncontrolled-rate cryopreservation of peripheral blood progenitor cells: a prospective multicenter study. Group for Cryobiology and Biology of Bone Marrow Transplantation (CBTMO), Spain.

Haematologica. 1998 Nov;83(11):1001-5.

Ex vivo manipulations of CD34+ peripheral blood progenitor cells.

Bone Marrow Transplant. 1996 Sep;18 Suppl 1:S5-7.

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Low cell concentration of cryopreserved autologous CD34+ peripheral blood progenitor cells does not impair hematopoietic recovery after transplantation.

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Low cell concentration of cryopreserved autologous CD34+ peripheral blood progenitor cells does not impair hematopoietic recovery after transplantation.

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