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[骨成形术和鼻-上颌窦开窗对上颌窦黏膜纤毛活动的影响:一项在兔身上的实验研究]

[The effect of ostioplasty and nasoantral window opening on mucociliary activity in the maxillary sinus: an experimental study in the rabbit].

作者信息

Güngör Atila, Poyrazoğlu Ethem, Narin Yavuz, Cekin Engin, Candan Hasan

机构信息

Department of Otolaryngology, Haydarpaşa Training Hospital of Gülhane Military Medical School, Istanbul, Turkey.

出版信息

Kulak Burun Bogaz Ihtis Derg. 2003 Apr;10(4):148-52.

Abstract

OBJECTIVES

We evaluated the effects of ostioplasty and nasoantral window opening techniques employed in endoscopic surgery procedures for maxillary sinuses on mucociliary activity in rabbits.

STUDY DESIGN

The study included 15 adult male New Zealand white rabbits (mean weight 3.5 kg). The animals were divided into three groups equal in number. Following a vertical incision in the midline, one group underwent ostioplasty to widen the natural ostium of the maxillary sinus; a new nasoantral window was opened in another group; the other group (controls) underwent only sinus exploration. Thirty days after surgery, mucociliary activity of the maxillary sinuses was evaluated scintigraphically.

RESULTS

Compared with the control group, mucociliary activity decreased significantly in both groups, showing a higher deterioration with the nasoantral window opening technique (p<0.001) than that with the ostioplasty technique (p<0.05).

CONCLUSION

Since both techniques have adverse effects on the mucociliary activity of the maxillary sinuses, ostioplasty and nasoantral window opening techniques should be reserved for patients in whom they are uniquely required.

摘要

目的

我们评估了上颌窦内镜手术中采用的造口术和鼻-鼻窦开窗技术对兔黏液纤毛活性的影响。

研究设计

该研究纳入了15只成年雄性新西兰白兔(平均体重3.5千克)。将动物平均分为三组。在中线做垂直切口后,一组进行造口术以扩大上颌窦自然开口;另一组开了一个新的鼻-鼻窦窗口;另一组(对照组)仅进行鼻窦探查。术后30天,通过闪烁显像评估上颌窦的黏液纤毛活性。

结果

与对照组相比,两组的黏液纤毛活性均显著降低,鼻-鼻窦开窗技术组的恶化程度高于造口术组(p<0.001),造口术组(p<0.05)。

结论

由于这两种技术对上颌窦的黏液纤毛活性均有不良影响,造口术和鼻-鼻窦开窗技术应仅用于有独特需求的患者。

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