Behrbohm H, Sydow K, Härtig W
Klinik und Poliklinik für Hals-Nasen-Ohrenkranheiten, Humboldt-Universität zu Berlin.
HNO. 1991 May;39(5):168-72.
The mucociliary clearance of the maxillary sinus mucosa was studied by 99mTc-SC in 38 healthy subjects. The mucociliary transport rate was relatively constant under physiological conditions so that it was possible to describe a normal range with a narrow variation. This range can be used to estimate the physiological responses of the mucociliary apparatus, and to define pathological disorders. In 3 cases we saw a slow clearance which has never been described before in the sinuses. In our experimental study we showed that the mucociliary activity of the sinuses is not only a mechanism to clean the mucosa, but is moreover a controlled system which can be activated by a physiological stimulus. After the stimulation the production of mucus and its outflow to the nose increased. Physiological and phylogenetic aspects of the existence of the sinuses in vertebrates and man are discussed.
用99m锝-硫胶体（99mTc-SC）对38名健康受试者的上颌窦黏膜的黏液纤毛清除功能进行了研究。在生理条件下，黏液纤毛转运速率相对恒定，因此有可能描述一个变化范围较窄的正常范围。该范围可用于评估黏液纤毛装置的生理反应，并界定病理紊乱情况。在3例患者中，我们观察到了鼻窦中从未有过描述的清除缓慢现象。在我们的实验研究中，我们表明鼻窦的黏液纤毛活动不仅是清洁黏膜的一种机制，而且还是一个可由生理刺激激活的控制系统。刺激后，黏液分泌及其向鼻腔的流出增加。讨论了脊椎动物和人类鼻窦存在的生理及系统发育方面的问题。
