[某些内源性化合物对神经元特异性烯醇化酶活性的调节]
[Regulation of the activity of neuron-specific enolase by certain endogenous compounds].
作者信息
Nazarian K B, Vaĭs M, Egorin R U, Kustzheba-Vuĭtsntska I, Petkevich Ia
出版信息
Biokhimiia. 1992 Dec;57(12):1827-33.
PMID:1294254
Abstract
The effects of glycolysis metabolites and some amino acids on the activity of bovine brain enolase have been studied. The inhibiting effect of glycolysis metabolites, of which two (2-phosphoglycolate and glyceraldehyde 3-phosphate) may be functionally significant, has been demonstrated. The action mechanisms of these compounds within a range of physiological concentrations as well as the combined effect of glyceraldehyde 3-phosphate and phosphoglyceromutase on enolase activity have been investigated.
摘要
研究了糖酵解代谢产物和一些氨基酸对牛脑烯醇化酶活性的影响。已证实糖酵解代谢产物具有抑制作用，其中两种（2-磷酸乙醇酸和3-磷酸甘油醛）可能具有功能意义。研究了这些化合物在生理浓度范围内的作用机制，以及3-磷酸甘油醛和磷酸甘油变位酶对烯醇化酶活性的联合作用。
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