Watanabe S
Department of Pediatric Dentistry, School of Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan.
Caries Res. 1992;26(6):423-7. doi: 10.1159/000261481.
The aim of this study was to evaluate the rates of salivary clearance at seven different locations in children. The diffusant was 1 mol/l KCl in a 1.0% agarose matrix, placed in small acrylic devices which could be fastened to the teeth with dental floss. The diffusion chambers were taken from the mouth at selected time intervals and the gels transferred quantitatively to flasks containing 400 ml of 100 ppm NaCl. The fluid was agitated intermittently for 1 h and analyzed for potassium by atomic absorption spectrophotometry. For 12 subjects (5 years of age), the clearance halftimes (the time for the initial potassium concentration to decrease by half) were lowest in the lower anterior lingual regions and were highest in the upper anterior buccal regions. When the salivary flow was stimulated, the clearance halftimes for the lower and upper anterior buccal sites in the 6 subjects without spaces between their anterior teeth were significantly higher than in the 6 subjects with spaces. The results show that the clearance halftime is longest for the upper anterior buccal site which is the site most prone to nursing bottle caries in the deciduous dentition.
本研究的目的是评估儿童七个不同部位的唾液清除率。扩散剂是1mol/L的KCl置于1.0%的琼脂糖基质中，放置在小型丙烯酸装置中，该装置可用牙线固定在牙齿上。在选定的时间间隔从口腔中取出扩散室，并将凝胶定量转移至含有400ml 100ppm NaCl的烧瓶中。液体间歇搅拌1小时，并用原子吸收分光光度法分析钾含量。对于12名5岁受试者，清除半衰期（初始钾浓度降低一半的时间）在下前舌部区域最低，在上前颊部区域最高。当刺激唾液分泌时，6名前牙无间隙受试者的上下前颊部部位的清除半衰期显著高于6名有间隙的受试者。结果表明，上乳前牙颊面是乳牙列中最易发生奶瓶龋的部位，其清除半衰期最长。
