Lewinsohn Peter M, Rohde Paul, Seeley John R, Klein Daniel N, Gotlib Ian H
Oregon Research Institute, Eugene 97403-1983, USA.
J Abnorm Psychol. 2003 Aug;112(3):353-63. doi: 10.1037/0021-843x.112.3.353.
The authors examined whether adolescent major depressive disorder (MDD) was associated with difficulties in young adult functioning and whether differences would remain significant after accounting for nonmood disorder, MDD recurrence, functioning in adolescence, or current mood state. A total of 941 participants were assessed twice during adolescence and at age 24. In unadjusted analyses, adolescent MDD was associated with most young adult functioning measures. Associations were not due to interactions with adolescent comorbidity, but differences in global functioning and mental health treatment appeared as a result of MDD recurrence. Accounting for levels of functioning in adolescence or for current depression at age 24 eliminated the remaining associations. The implications of these findings for efforts to prevent MDD in adolescence are discussed.
作者们研究了青少年重度抑郁症（MDD）是否与青年期功能障碍有关，以及在考虑非情绪障碍、MDD复发、青少年期功能或当前情绪状态后，差异是否仍具有显著性。共有941名参与者在青少年期和24岁时接受了两次评估。在未经调整的分析中，青少年MDD与大多数青年期功能指标相关。这些关联并非由于与青少年共病的相互作用，但全球功能和心理健康治疗方面的差异是MDD复发的结果。考虑青少年期的功能水平或24岁时的当前抑郁状况后，消除了其余的关联。讨论了这些发现对预防青少年MDD努力的意义。
