作为前瞻性自杀未遂预测因素的轴I和轴II障碍：来自协作性纵向人格障碍研究的结果
Axis I and axis II disorders as predictors of prospective suicide attempts: findings from the collaborative longitudinal personality disorders study.
作者信息
Yen Shirley, Shea M Tracie, Pagano Maria, Sanislow Charles A, Grilo Carlos M, McGlashan Thomas H, Skodol Andrew E, Bender Donna S, Zanarini Mary C, Gunderson John G, Morey Leslie C
机构信息
Department of Psychiatry and Human Behavior, Brown Medical School, Brown University, Providence, Rhode Island 02906, USA.
出版信息
J Abnorm Psychol. 2003 Aug;112(3):375-81. doi: 10.1037/0021-843x.112.3.375.
Abstract
This study examined diagnostic predictors of prospectively observed suicide attempts in a personality disorder (PD) sample. During 2 years of follow-up, 58 participants (9%) reported at least 1 definitive suicide attempt. Predictors that were examined include 4 PD diagnoses and selected Axis I diagnoses (baseline and course). Multivariate logistic regression analyses indicated that baseline borderline personality disorder (BPD) and drug use disorders significantly predicted prospective suicide attempts. Controlling for baseline BPD diagnosis, proportional hazards analyses showed that worsening in the course of major depressive disorder (MDD) and of substance use disorders in the month preceding the attempt were also significant predictors. Therefore, among individuals diagnosed with PDs. exacerbation of Axis I conditions, particularly MDD and substance use, heightens risk for a suicide attempt.
摘要
本研究考察了人格障碍（PD）样本中前瞻性观察到的自杀未遂的诊断预测因素。在2年的随访期间，58名参与者（9%）报告至少有1次明确的自杀未遂。所考察的预测因素包括4种人格障碍诊断和选定的轴I诊断（基线和病程）。多变量逻辑回归分析表明，基线边缘型人格障碍（BPD）和药物使用障碍显著预测前瞻性自杀未遂。在控制基线BPD诊断后，比例风险分析显示，在自杀未遂前一个月，重度抑郁症（MDD）病程的恶化以及物质使用障碍的恶化也是显著的预测因素。因此，在被诊断为人格障碍的个体中，轴I疾病的加重，尤其是MDD和物质使用，会增加自杀未遂的风险。
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