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微波断层扫描测温中图像准确性的提高:体模实验经验

Image accuracy improvements in microwave tomographic thermometry: phantom experience.

作者信息

Meaney P M, Paulsen K D, Fanning M W, Li D, Fang Q

机构信息

Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.

出版信息

Int J Hyperthermia. 2003 Sep-Oct;19(5):534-50. doi: 10.1080/0265673031000082386.

DOI:10.1080/0265673031000082386
PMID:12944168
Abstract

Evaluation of a laboratory-scale microwave imaging system for non-invasive temperature monitoring has previously been reported with good results in terms of both spatial and temperature resolution. However, a new formulation of the reconstruction algorithm in terms of the log-magnitude and phase of the electric fields has dramatically improved the ability of the system to track the temperature-dependent electrical conductivity distribution. This algorithmic enhancement was originally implemented as a way of improving overall imaging capability in cases of large, high contrast permittivity scatterers, but has also proved to be sensitive to subtle conductivity changes as required in thermal imaging. Additional refinements in the regularization procedure have strengthened the reliability and robustness of image convergence. Imaging experiments were performed for a single heated target consisting of a 5.1 cm diameter PVC tube located within 15 and 25 cm diameter monopole antenna arrays, respectively. The performance of both log-magnitude/phase and complex-valued reconstructions when subjected to four different regularization schemes has been compared based on this experimental data. The results demonstrate a significant accuracy improvement (to 0.2 degrees C as compared with 1.6 degrees C for the previously published approach) in tracking thermal changes in phantoms where electrical properties vary linearly with temperature over a range relevant to hyperthermia cancer therapy.

摘要

先前已有关于实验室规模的用于非侵入式温度监测的微波成像系统的评估报告,其在空间分辨率和温度分辨率方面均取得了良好结果。然而,一种基于电场对数幅度和相位的重建算法新公式显著提高了该系统追踪与温度相关的电导率分布的能力。这种算法增强最初是作为一种在大尺寸、高对比度介电常数散射体情况下提高整体成像能力的方法而实现的,但事实证明它对热成像所需的细微电导率变化也很敏感。正则化过程中的进一步改进增强了图像收敛的可靠性和稳健性。针对单个加热目标进行了成像实验,该目标由分别位于直径为15厘米和25厘米的单极天线阵列内的一根直径5.1厘米的PVC管组成。基于该实验数据,比较了对数幅度/相位和复值重建在四种不同正则化方案下的性能。结果表明,在追踪与热疗癌症治疗相关的温度范围内电特性随温度线性变化的体模中的热变化时,精度有显著提高(与先前发表的方法的1.6摄氏度相比提高到了0.2摄氏度)。

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