Wold Peter B, Fletcher Joel G, Johnson C Daniel, Sandborn William J
Department of Diagnostic Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Radiology. 2003 Oct;229(1):275-81. doi: 10.1148/radiol.2291020877. Epub 2003 Aug 27.
A feasibility study was conducted to evaluate two biphasic computed tomographic (CT) enterography protocols, a noninvasive CT technique with water administered perorally and CT enteroclysis with methylcellulose administered through a nasojejunal tube, in 23 patients known or suspected to have Crohn disease. Results were compared with the results of fluoroscopic small bowel examination and terminal ileoscopy for the detection of active Crohn disease in the terminal ileum. Luminal distention did not differ significantly between the two CT protocols. Arterial phase imaging was noncontributory in 22 of 23 cases. The noninvasive peroral water CT enterography protocol had similar accuracy (12 of 15 cases, 80%) for enabling the detection of active Crohn disease in comparison with CT enteroclysis with nasojejunal tube (seven of eight, 88%) and fluoroscopic small bowel examination (17 of 23, 74%). No fistulas were missed with use of either CT technique. The authors conclude that noninvasive peroral portal venous phase CT enterography with use of water is an accurate and feasible technique for detecting active small bowel inflammation in patients with Crohn disease.
对23例已知或疑似患有克罗恩病的患者进行了一项可行性研究，以评估两种双期计算机断层扫描（CT）小肠造影方案，一种是口服水的非侵入性CT技术，另一种是通过鼻空肠管注入甲基纤维素的CT小肠灌肠法。将结果与荧光透视小肠检查和末端回肠镜检查结果进行比较，以检测末端回肠的活动性克罗恩病。两种CT方案之间的管腔扩张情况无显著差异。23例中有22例的动脉期成像无诊断价值。与经鼻空肠管CT小肠灌肠法（8例中的7例，88%）和荧光透视小肠检查（23例中的17例，74%）相比，口服水的非侵入性CT小肠造影方案在检测活动性克罗恩病方面具有相似的准确性（15例中的12例，80%）。两种CT技术均未漏诊瘘管。作者得出结论，使用水的非侵入性口服门静脉期CT小肠造影是检测克罗恩病患者活动性小肠炎症的一种准确且可行的技术。
