螺双六氢嘧啶的生物制药研究。
Biopharmaceutical studies of spirobishexahydropyrimidine.
作者信息
Alam M, Ahmad M, Rasheed A, Ahmad A
机构信息
Department of Pharmacy, University of the Punjab, Lahore, Pakistan.
出版信息
Indian J Exp Biol. 1992 Dec;30(12):1181-3.
PMID:1294482
Abstract
Oral administration of spirobishexahydropyrimidine showed an increase in the activity of serum transaminases, lactate dehydrogenase and alkaline phosphatase. Biological half life and other pharmacokinetic parameters showed rapid absorption and slow elimination of the drug.
摘要
口服螺双六氢嘧啶会使血清转氨酶、乳酸脱氢酶和碱性磷酸酶的活性增加。生物半衰期和其他药代动力学参数表明该药物吸收迅速且消除缓慢。
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