Wirrell Elaine C
Department of Pediatrics, University of Calgary, AB, Canada.
Can J Neurol Sci. 2003 Aug;30(3):184-8. doi: 10.1017/s0317167100002560.
Absence seizures may be seen in a variety of epileptic syndromes in childhood. Identification of the specific syndrome is important to determine medical prognosis. With childhood absence epilepsy, approximately two thirds of children can be expected to enter long-term remission, while in juvenile absence epilepsy, seizure control is often achieved, however, lifelong treatment is usually required. Other absence syndromes have a poorer prognosis, with lower rates of seizure control and remission. Psychosocial outcome is often poor, even in patients with more benign forms of absence epilepsy. Remission of epilepsy does not preclude psychosocial morbidity.
失神发作可见于儿童期多种癫痫综合征。明确具体综合征对于判断医学预后很重要。对于儿童失神癫痫,约三分之二的患儿有望进入长期缓解期,而在青少年失神癫痫中,虽常能实现发作控制,但通常需要终身治疗。其他失神综合征预后较差,发作控制和缓解率较低。即使是失神癫痫较良性形式的患者,其社会心理结局往往也较差。癫痫缓解并不排除社会心理疾病的发生。