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脉络膜黑色素瘤的预后因素:76例眼球摘除病例的解剖临床回顾性统计研究

[Prognostic factors of choroidal melanoma: an anatomo-clinical retrospective and statistical study of 76 enucleated cases].

作者信息

Panigel K, Hedelin G, Speeg-Schatz C, Sahel J, Brini A

机构信息

Clinique Ophtalmologique, CHRU, Strasbourg.

出版信息

J Fr Ophtalmol. 1992;15(6-7):410-4.

PMID:1294598
Abstract

The authors report the results of a retrospective study of 76 patients enucleated for a choroidal melanoma, in whom prognostic factors of survival were studied. The presence of metastasis at the time of diagnosis, the size of the tumor and the epithelioid cellular type are the most pejorative factors (though statistically not significant). A peak mortality can be observed between the second and the fourth year after enucleation. A predominance of the liver metastases is clearly established (75% of the metastases observed in our sample). We observed a majority of small tumors (40%) of spindle cell type (50%).

摘要

作者报告了一项对76例因脉络膜黑色素瘤而接受眼球摘除术患者的回顾性研究结果,研究了其生存预后因素。诊断时存在转移、肿瘤大小和上皮样细胞类型是最不利的因素(尽管在统计学上不显著)。眼球摘除术后第二至第四年可观察到死亡率高峰。肝转移占主导地位已明确确立(在我们的样本中观察到的转移中有75%)。我们观察到大多数为小肿瘤(40%),纺锤细胞类型占50%。

相似文献

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[Prognostic factors of choroidal melanoma: an anatomo-clinical retrospective and statistical study of 76 enucleated cases].脉络膜黑色素瘤的预后因素:76例眼球摘除病例的解剖临床回顾性统计研究
J Fr Ophtalmol. 1992;15(6-7):410-4.
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Prognostic factors for survival after enucleation for choroidal and ciliary body melanomas.脉络膜和睫状体黑色素瘤眼球摘除术后生存的预后因素。
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The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24.脉络膜黑色素瘤协作组(COMS)关于大脉络膜黑色素瘤眼球摘除术前放疗的随机试验:IV. 十年死亡率研究结果及预后因素。COMS报告第24号。
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[Follow-up after enucleation in choroid melanoma].脉络膜黑色素瘤眼球摘除术后的随访
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[Prognostic relevance of histopathologic parameters in malignant melanoma of the choroid using the pTNM classification].
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In malignant choroidal melanoma will a delay in radical treatment influence prognosis?
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 1):49-53.
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The natural history of malignant melanoma of the choroid: small vs large tumors.脉络膜恶性黑色素瘤的自然病史:小肿瘤与大肿瘤对比
Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1975 Mar-Apr;79(2):OP310-20.

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Am J Pathol. 1998 Apr;152(4):855-63.