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脉络膜黑色素瘤的预后因素:76例眼球摘除病例的解剖临床回顾性统计研究

[Prognostic factors of choroidal melanoma: an anatomo-clinical retrospective and statistical study of 76 enucleated cases].

作者信息

Panigel K, Hedelin G, Speeg-Schatz C, Sahel J, Brini A

机构信息

Clinique Ophtalmologique, CHRU, Strasbourg.

出版信息

J Fr Ophtalmol. 1992;15(6-7):410-4.

PMID:1294598
Abstract

The authors report the results of a retrospective study of 76 patients enucleated for a choroidal melanoma, in whom prognostic factors of survival were studied. The presence of metastasis at the time of diagnosis, the size of the tumor and the epithelioid cellular type are the most pejorative factors (though statistically not significant). A peak mortality can be observed between the second and the fourth year after enucleation. A predominance of the liver metastases is clearly established (75% of the metastases observed in our sample). We observed a majority of small tumors (40%) of spindle cell type (50%).

摘要

作者报告了一项对76例因脉络膜黑色素瘤而接受眼球摘除术患者的回顾性研究结果,研究了其生存预后因素。诊断时存在转移、肿瘤大小和上皮样细胞类型是最不利的因素(尽管在统计学上不显著)。眼球摘除术后第二至第四年可观察到死亡率高峰。肝转移占主导地位已明确确立(在我们的样本中观察到的转移中有75%)。我们观察到大多数为小肿瘤(40%),纺锤细胞类型占50%。

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