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脉络膜黑色素瘤眼球摘除术后的随访

[Follow-up after enucleation in choroid melanoma].

作者信息

Gliem H, Gelb W, Wolf T, Trinkmann R

出版信息

Fortschr Ophthalmol. 1989;86(3):242-4.

PMID:2759535
Abstract

We report on 31 patients who underwent enucleation between 1976 and 1984 for uveal melanoma and had a mean follow-up of 107 months. There was no irradiation to the globe or orbit prior to enucleation, which was done under general anesthesia. Histology showed that: the average diameter of the tumors was 10.6 mm and the average height 6.2 mm. There were 3 cases of spindle-cell A-type tumors, 19 of spindle-cell B, 2 of mixed cell types, and 7 cases of mixed cell types with epithelioid cell dominance or epithelioid cell tumors. In September 1988, 9 patients (29%) had died as of a result of metastases from the melanoma; 4 patients who died were found to have another malignant tumor; 1 patient died due to cerebral apoplexia; 1 patient died 8 days after enucleation due to unknown causes. The survival curve was based on the Kaplan-Meier method.

摘要

我们报告了1976年至1984年间因葡萄膜黑色素瘤接受眼球摘除术的31例患者,平均随访时间为107个月。在全身麻醉下进行眼球摘除术之前,未对眼球或眼眶进行放疗。组织学检查显示:肿瘤平均直径为10.6毫米,平均高度为6.2毫米。有3例梭形细胞A型肿瘤,19例梭形细胞B型,2例混合细胞类型,以及7例以上皮样细胞为主的混合细胞类型或上皮样细胞瘤。截至1988年9月,9例患者(29%)因黑色素瘤转移而死亡;4例死亡患者被发现患有另一种恶性肿瘤;1例患者死于脑中风;1例患者在眼球摘除术后8天因不明原因死亡。生存曲线采用Kaplan-Meier法绘制。

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