Gliem H, Gelb W, Wolf T, Trinkmann R
Fortschr Ophthalmol. 1989;86(3):242-4.
We report on 31 patients who underwent enucleation between 1976 and 1984 for uveal melanoma and had a mean follow-up of 107 months. There was no irradiation to the globe or orbit prior to enucleation, which was done under general anesthesia. Histology showed that: the average diameter of the tumors was 10.6 mm and the average height 6.2 mm. There were 3 cases of spindle-cell A-type tumors, 19 of spindle-cell B, 2 of mixed cell types, and 7 cases of mixed cell types with epithelioid cell dominance or epithelioid cell tumors. In September 1988, 9 patients (29%) had died as of a result of metastases from the melanoma; 4 patients who died were found to have another malignant tumor; 1 patient died due to cerebral apoplexia; 1 patient died 8 days after enucleation due to unknown causes. The survival curve was based on the Kaplan-Meier method.
我们报告了1976年至1984年间因葡萄膜黑色素瘤接受眼球摘除术的31例患者，平均随访时间为107个月。在全身麻醉下进行眼球摘除术之前，未对眼球或眼眶进行放疗。组织学检查显示：肿瘤平均直径为10.6毫米，平均高度为6.2毫米。有3例梭形细胞A型肿瘤，19例梭形细胞B型，2例混合细胞类型，以及7例以上皮样细胞为主的混合细胞类型或上皮样细胞瘤。截至1988年9月，9例患者（29%）因黑色素瘤转移而死亡；4例死亡患者被发现患有另一种恶性肿瘤；1例患者死于脑中风；1例患者在眼球摘除术后8天因不明原因死亡。生存曲线采用Kaplan-Meier法绘制。
