Doherty Gerard M
Division of Endocrine Surgery, Section of Endocrine Surgery, Department of Surgery, University of Michigan School of Medicine, 2920 Taubman Center, Ann Arbor, MI 48109, USA.
Surg Oncol. 2003 Aug;12(2):135-43. doi: 10.1016/s0960-7404(03)00038-0.
Duodenopancreatic endocrine tumors are the most frequently lethal part of MEN-1. The management of these patients is complicated by the variable hormonal function of the tumors, and the often indolent but occasionally lethal nature of the tumors. This article reviews our current approach to the diagnosis, surveillance and management of these patients.
十二指肠胰腺内分泌肿瘤是多内分泌腺瘤病1型(MEN-1)中最常导致死亡的部分。这些患者的治疗因肿瘤激素功能的变化以及肿瘤通常进展缓慢但偶尔具有致命性的特点而变得复杂。本文综述了我们目前对这些患者的诊断、监测及治疗方法。