舒张期频谱脉冲组织多普勒成像：一种增强我们对左心室舒张期松弛的理解和评估的工具。

Spectral pulsed tissue Doppler imaging in diastole: a tool to increase our insight in and assessment of diastolic relaxation of the left ventricle.

作者信息

De Boeck Bart W l, Cramer Maarten-Jan M, Oh Jae K, van der Aa Ronald P L M, Jaarsma Wybren

机构信息

Department of Non-invasive Cardiac Imaging, University Medical Centre, Utrecht, The Netherlands.

出版信息

Am Heart J. 2003 Sep;146(3):411-9. doi: 10.1016/S0002-8703(03)00322-3.

DOI:10.1016/S0002-8703(03)00322-3

PMID:12947357

Abstract

BACKGROUND

Conventional Doppler echocardiography offers an indirect assessment of left ventricular (LV) diastolic function, hampered by preload dependency. Tissue Doppler imaging (TDI) is a tool to study diastolic function in a more direct and less preload-dependent manner.

METHODS

The Medline database has been searched for literature on TDI for the analysis of diastolic function. A secondary search reviewed the relevant references related to TDI or diastolic function in general.

RESULTS

TDI measures myocardial velocities with a high temporal and velocity resolution but lacks spatial information. In particular, the velocity of early diastolic wall motion (E(m)) and its timing are promising indices of local myocardial relaxation. E(m) at the mitral annulus offers fair estimates of ventricular relaxation, relatively independent of preload and systolic function. Combined with early transmitral flow velocity (E), detection of pseudo-normalized filling patterns and estimation of filling pressures are enhanced by E/E(m).

CONCLUSION

TDI has an emerging role in the study and assessment of diastolic function. However, TDI-derived information needs to be integrated with other echocardiographic data because single diagnostic accuracy remains unsatisfactory.

摘要

背景

传统多普勒超声心动图可对左心室舒张功能进行间接评估，但受前负荷依赖性的限制。组织多普勒成像（TDI）是一种以更直接且受前负荷影响较小的方式研究舒张功能的工具。

方法

检索了Medline数据库中有关TDI用于舒张功能分析的文献。二次检索全面回顾了与TDI或一般舒张功能相关的参考文献。

结果

TDI能够以高时间和速度分辨率测量心肌速度，但缺乏空间信息。特别是，舒张早期室壁运动速度（E(m)）及其时间是局部心肌松弛的有前景的指标。二尖瓣环处的E(m)可对心室松弛进行合理估计，相对独立于前负荷和收缩功能。结合早期二尖瓣血流速度（E），E/E(m)可增强对假性正常化充盈模式的检测及充盈压力的估计。