Bakshi Dinkar, Seth A, Narula M K, Shankar R
Department of Paediatrics, Lady Hardinge Medical College, Delhi, India.
J Pediatr Endocrinol Metab. 2003 Jul-Aug;16(6):843-9. doi: 10.1515/jpem.2003.16.6.843.
Ultrasonographic measurement of thyroid volume is increasingly being used to assess prevalence of iodine deficiency in a community.
To assess thyroid volume by ultrasonography in normal Delhi children, and compare them with the recently adopted WHO reference standards.
One hundred and three children aged of 6-10 years were enrolled from the paediatric outpatient clinic in a prospective study. Thyroid volume was estimated by ultrasound, and urinary iodine levels were measured for all subjects by spot urine samples.
Goitre prevalence was 24.3% on clinical assessment. Urinary iodine levels fell in the range of mild to moderate deficiency in 61% of the children. None of the children met the WHO recommended ultrasonographic criteria for goitre (thyroid volume >97th percentile of the reference standards), when WHO age-specific norms were used for comparison. On applying body surface area (BSA)-specific norms, only two children were classified as having goitre.
The WHO standards for thyroid volume by ultrasonography tended to underestimate goitre prevalence.