Kraft Peter, Horvath Steve
Department of Biostatistics, UCLA School of Public Health, Box 951772 51-236C CHS, Los Angeles, CA 90095-1772, USA.
Trends Biotechnol. 2003 Sep;21(9):377-8. doi: 10.1016/S0167-7799(03)00191-4.
A recent publication has shown that a significant portion of gene expression levels are under genetic control in different organisms, that there are hotspot regions in the genome that control the expression of many other genes, and how gene expression data can be used to localize genes that affect clinical traits.
最近的一项研究表明,在不同生物体中,很大一部分基因表达水平受遗传控制,基因组中存在控制许多其他基因表达的热点区域,以及如何利用基因表达数据来定位影响临床特征的基因。