利用DNA微阵列数据理解耐辐射球菌的抗电离辐射能力。

Using DNA microarray data to understand the ionizing radiation resistance of Deinococcus radiodurans.

作者信息

Edwards Jeremy S, Battista John R

机构信息

Chemical Engineering, University of Delaware, Newark, DE 19716, USA.

出版信息

Trends Biotechnol. 2003 Sep;21(9):381-2. doi: 10.1016/S0167-7799(03)00196-3.

DOI:10.1016/S0167-7799(03)00196-3

PMID:12948669

Abstract

In a recent paper, Liu et al. documented the changes in gene expression as stationary phase Deinococcus radiodurans cultures recover from acute exposure to gamma radiation. Given that the biochemical details of the response of D. radiodurans to ionizing radiation are poorly understood, this work represents an important first step towards achieving an understanding of the ionizing radiation resistance in this species.

摘要

在最近的一篇论文中，刘等人记录了嗜放射球菌静止期培养物从急性γ辐射暴露中恢复时基因表达的变化。鉴于对嗜放射球菌对电离辐射反应的生化细节了解甚少，这项工作是朝着理解该物种的抗电离辐射能力迈出的重要第一步。