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[更年期的口腔症状。一项患病率研究]

[Oral symptoms in the climacteric. A prevalence study].

作者信息

Trombelli L, Mandrioli S, Zangari F, Saletti C, Calura G

机构信息

Istituto di Clinica Odontoiatrica, Università degli Studi di Ferrara.

出版信息

Minerva Stomatol. 1992 Nov;41(11):507-13.

PMID:1294873
Abstract

The female climacteric is attributed to physiological ovarian failure with the consequent decrease in the secretions of oestrogen, progestones and androgens. Numerous metabolic, psychological and physical changes have been associated with this event. Oral discomfort, including the burning mouth syndrome and the dry mouth syndrome, has been described as a menopausal symptom. However, the relationship between the hormonal changes related to climacteric and the onset of oral discomfort is still controversial. The purpose of the present study was to evaluate the prevalence of oral symptoms, with particular regard to burning sensation, xerostomia, altered taste and recurrent oral ulcerations. The relationship between oral and climacteric symptoms and psychological status of the patients was also evaluated. A questionnaire was administered to 136 women (mean age: 51.2 years, range 40-62) being consecutively referred to the University Hospital Menopause Clinic from October 1991 to March 1992. The questionnaire included informations regarding menopausal state, oral symptoms, drug assumption, wearing of partial or total dentures, parafunctions (lip and cheek biting, bruxism, tongue thrusting). Climacteric symptoms including flushes/sweats, palpitations, headache, arthralgia/myalgia, vaginal dryness, decreased concentration, tiredness, decreased libido, insomnia, vertigo were evaluated. Visual analogue scale (VAS) was used where appropriate. Information regarding the alteration of the psychological status was collected by means of the Hospital Anxiety and Depression Scale Statistical analysis was performed by chi 2 test or Fisher's Exact Probability Test and Mann-Whitney U-test. The level of significance accepted was 5%. The subjects in this study were divided into two groups on the basis of their answers to the questionnaire: group I (no. 39), premenopausal women; group II (no. 97), menopausal women.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

女性更年期归因于生理性卵巢功能衰竭,随之而来的是雌激素、孕激素和雄激素分泌减少。许多代谢、心理和身体变化都与这一事件相关。口腔不适,包括灼口综合征和口干综合征,已被描述为一种更年期症状。然而,与更年期相关的激素变化和口腔不适的发作之间的关系仍存在争议。本研究的目的是评估口腔症状的患病率,尤其关注烧灼感、口干、味觉改变和复发性口腔溃疡。还评估了口腔和更年期症状与患者心理状态之间的关系。对1991年10月至1992年3月连续转诊至大学医院更年期诊所的136名女性(平均年龄:51.2岁,范围40 - 62岁)进行了问卷调查。问卷包括有关更年期状态、口腔症状、药物服用、佩戴局部或全口假牙、异常功能(咬唇和咬颊、磨牙症、伸舌)的信息。评估了更年期症状,包括潮热/盗汗、心悸、头痛、关节痛/肌痛、阴道干燥、注意力下降、疲劳、性欲减退、失眠、眩晕。在适当情况下使用视觉模拟量表(VAS)。通过医院焦虑和抑郁量表收集有关心理状态改变的信息。采用卡方检验或Fisher精确概率检验以及曼 - 惠特尼U检验进行统计分析。接受的显著性水平为5%。根据问卷答案,本研究中的受试者分为两组:第一组(39人),绝经前女性;第二组(97人),绝经后女性。(摘要截断于250字)

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