Shimizu Chika, Kuriyama Tomoari, Williams David W, Karasawa Tadahiro, Inoue Katsumi, Nakagawa Kiyomasa, Yamamoto Etsuhide
Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Apr;105(4):445-51. doi: 10.1016/j.tripleo.2007.11.030.
The aim of this study was to determine if there was a significant association between the presence of altered mouth and taste sensations with oral carriage of yeasts and to assess the factors that influence the yeast carriage.
The oral and dental status including unstimulated (USFR) and stimulated (SSFR) whole salivary flow rates of a total of 509 subjects was recorded. Saliva specimens were collected for microbiologic examination. Multiple logistic regression analysis was performed to identify any factors that were significantly associated with the prevalence of oral yeasts.
Old age, clinical signs of oral dryness, denture wearing, and a reduction in USFR increased the prevalence of yeasts, whereas patient gender, levels of dentition, the sensation of dry or burning mouth, taste disorders, and SSFR were not associated with increased prevalence of oral yeasts.
An increased prevalence of oral yeasts was not found to relate to changes in mouth sensation alone. Other factors, most notably patient age, the wearing of dentures, clinical signs of oral dryness, and salivary flow rate under rest conditions, were, however, found to be closely associated with oral yeast carriage.
本研究旨在确定口腔和味觉改变与酵母口腔携带之间是否存在显著关联，并评估影响酵母携带的因素。
记录了总共509名受试者的口腔和牙齿状况，包括非刺激性（USFR）和刺激性（SSFR）全唾液流速。收集唾液标本进行微生物学检查。进行多因素逻辑回归分析以确定与口腔酵母流行率显著相关的任何因素。
老年、口腔干燥的临床体征、佩戴假牙以及USFR降低会增加酵母的流行率，而患者性别、牙列水平、口腔干燥或灼痛感觉、味觉障碍和SSFR与口腔酵母流行率增加无关。
未发现口腔酵母流行率增加仅与口腔感觉变化有关。然而，发现其他因素，最显著的是患者年龄、佩戴假牙、口腔干燥的临床体征和静息状态下的唾液流速，与口腔酵母携带密切相关。
