Salditt Tim
Institüt für Röntgenphysik, Universität Göttingen, Geiststrasse 11, D-37037 Göttingen, Germany.
Curr Opin Struct Biol. 2003 Aug;13(4):467-78. doi: 10.1016/s0959-440x(03)00113-1.
Oriented lipid membranes deposited on solid substrates offer unique experimental opportunities to study lipid bilayer structure and lipid-peptide interaction in suitable model systems. In particular, modern interface-sensitive X-ray and neutron scattering methods can be used to probe the short-range order and molecular conformations of peptides and lipids in the fluid state of the bilayer.
沉积在固体基质上的定向脂质膜为在合适的模型系统中研究脂质双层结构和脂质-肽相互作用提供了独特的实验机会。特别是,现代界面敏感的X射线和中子散射方法可用于探测双层流体状态下肽和脂质的短程有序性和分子构象。