[移植物抗宿主反应导致的免疫缺陷。胸腺在恢复免疫中的胸腺外效应]
[Immunodeficiency caused by graft versus host reaction. Extra-thymic effect of thymus in restoring immunity].
作者信息
Lang P, Bierre V, Baron C, Rostoker G, Weil B
机构信息
INSERM U 139, Hôpital Henri-Mondor, Créteil.
出版信息
Presse Med. 1992 Dec 2;21(41):1961.
PMID:1294951
Abstract
Cell-mediated immunity in lethally irradiated graft-versus-host mice can be restored after repopulation with syngeneic bone marrow cells and thymus grafting. The thymus is not only required for the maturation of T lymphocytes, but also for the inhibition of a radioresistant mechanism resulting in lymphoid cell rejection.
摘要
在接受致死性照射的移植物抗宿主小鼠中，同基因骨髓细胞再植和胸腺移植后，细胞介导的免疫功能可以恢复。胸腺不仅是T淋巴细胞成熟所必需的，而且对于抑制导致淋巴细胞排斥的抗辐射机制也是必需的。
Zotero 插件