S'iakste N I
Tsitologiia. 1992;34(9):3-16.
Data about the changes of the cell nucleus structure at different levels of its organization are summarized in the review. The data about the change of the DNA break number during the cycle and in resting state are presented and the role of the changes of the repair efficiency in this process is discussed. The changes of the chromatin protein spectrum, the chromatin structure at nucleosomal and supranucleosomal levels, the DNA superhelicity, topoisomerase activity, nuclear matrix composition and structure are discussed as well. The nucleus structure during the S-phase and mitosis and the cycle-related changes of the chromatin structure in lower eukaryotes are reviewed separately.
本综述总结了关于细胞核结构在不同组织水平变化的数据。文中呈现了细胞周期和静止状态下DNA断裂数变化的数据，并讨论了修复效率变化在此过程中的作用。还讨论了染色质蛋白质谱的变化、核小体和超核小体水平的染色质结构、DNA超螺旋、拓扑异构酶活性、核基质组成和结构的变化。分别综述了S期和有丝分裂期间的细胞核结构以及低等真核生物中与细胞周期相关的染色质结构变化。
