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嗜稻黄单胞菌感染所致菌血症和鼻窦炎

Bacteraemia and sinusitis due to Flavimonas oryzihabitans infection.

作者信息

Lejbkowicz Flavio, Belavsky Larissa, Kudinsky Raya, Gery Raphael

机构信息

Department of Clinical Microbiology, Western Galilee Hospital, Nahariya, Israel.

出版信息

Scand J Infect Dis. 2003;35(6-7):411-4. doi: 10.1080/00365540310012208.

Abstract

Flavimonas oryzihabitans is rarely reported as a pathogen in human infections and is related to opportunistic infection. Previously reported cases of infections caused by this bacterium were nosocomially acquired, including bacteraemia in critically ill patients, catheter-related infection, and peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. Three cases of F. oryzihabitans infection are presented, 1 of which was sinusitis and 2 were nosocomially acquired bacteraemia. To the authors' knowledge, this is the first reported case of sinusitis infection due to F. oryzihabitans induced by prosthetic material. Isolates from the 2 bacteraemic patients were susceptible to tazobactam, ceftazidime, cefepime, aztreonam, gentamicin, amikacin, imipenem, ciprofloxacin and levofloxacin, but resistant to cephazolin, cefuroxime and trimethoprim. The isolate from the sinus was susceptible to gentamicin, amikacin, tetracycline, ciprofloxacin and levofloxacin. After appropriate treatment all the patients recovered and no longer showed signs of the pathogen.

摘要

栖稻黄单胞菌作为人类感染的病原体鲜有报道,且与机会性感染有关。先前报道的由该细菌引起的感染病例均为医院获得性感染,包括重症患者的菌血症、导管相关感染以及持续性非卧床腹膜透析患者的腹膜炎。本文报告了3例栖稻黄单胞菌感染病例,其中1例为鼻窦炎,2例为医院获得性菌血症。据作者所知,这是首例因假体材料诱发的栖稻黄单胞菌引起的鼻窦炎感染病例。2例菌血症患者的分离菌株对他唑巴坦、头孢他啶、头孢吡肟、氨曲南、庆大霉素、阿米卡星、亚胺培南、环丙沙星和左氧氟沙星敏感,但对头孢唑林、头孢呋辛和甲氧苄啶耐药。鼻窦分离菌株对庆大霉素、阿米卡星、四环素、环丙沙星和左氧氟沙星敏感。经过适当治疗,所有患者均康复,且未再出现该病原体感染迹象。

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