用于更好理解免疫功能的生物信息学策略。

Bioinformatic strategies for better understanding of immune function.

作者信息

Petrovsky Nikolai, Schönbach Christian, Brusic Vladimir

机构信息

Centre for Medical Informatics, Division of Science and Design, University of Canberra, Bruce ACT 2617, Australia.

出版信息

In Silico Biol. 2003;3(4):411-6.

PMID:12954084

Abstract

Novartis Foundation sponsored a Symposium which brought together a group of experimental immunologists, theoretical immunologists, and bioinformaticians to discuss the new field of immunoinformatics. The discussion focused on immunological databases, antigen processing and presentation, immunogenomics, host-pathogen interactions, and mathematical modelling of the immune system. A main conclusion of the meeting is the critical role played by immunoinformatics in current immunology research. In particular, immunoinformatics provides a foundation for the emerging fields of systems immunology and immunogenomics.

摘要

诺华基金会主办了一次研讨会，汇聚了一批实验免疫学家、理论免疫学家和生物信息学家，共同探讨免疫信息学这一新兴领域。讨论集中在免疫数据库、抗原加工与呈递、免疫基因组学、宿主-病原体相互作用以及免疫系统的数学建模等方面。会议的一个主要结论是免疫信息学在当前免疫学研究中发挥的关键作用。特别是，免疫信息学为系统免疫学和免疫基因组学等新兴领域提供了基础。