Xu X G, Chao T C
Nuclear Engineering and Engineering Physics Programs, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
Cancer Biother Radiopharm. 2003 Jun;18(3):431-6. doi: 10.1089/108497803322285189.
Assessment of organ doses from internally deposited radionuclides involves the use of predetermined specific absorbed fractions (SAFs). Many tabulations of SAFs have been derived from Monte Carlo transport simulations using stylized computational models that are not fully realistic of human internal organ anatomy. This paper presents the results of a study to calculate SAFs in the gastrointestinal (GI) tract using a recently developed tomographic model VIP-Man and the EGS4 Monte Carlo radiation transport code. Results show that, for some energies and source-target combinations, considerable discrepancies exist between these results and those from earlier studies, suggesting a need to evaluate existing data carefully by comparison with realistic models.
评估体内沉积放射性核素产生的器官剂量需要使用预先确定的特定吸收分数（SAF）。许多SAF表格是通过使用程式化计算模型的蒙特卡罗输运模拟得出的，这些模型并不能完全真实地反映人体内部器官的解剖结构。本文介绍了一项研究的结果，该研究使用最近开发的断层模型VIP-Man和EGS4蒙特卡罗辐射输运代码来计算胃肠道（GI）中的SAF。结果表明，对于某些能量和源-靶组合，这些结果与早期研究的结果之间存在相当大的差异，这表明需要通过与实际模型进行比较来仔细评估现有数据。
