Bufo P, Minervini M I, Frassanito F
Istituto di Anatomia ed Istologia patologica, Università degli Studi di Bari.
Boll Soc Ital Biol Sper. 1992 Oct;68(10):625-31.
Eight cases of primary gastric lymphomas have been investigated by AgNORs method to individualize the patterns of distribution of NORs. Modifying and exemplifying the scheme of Nikicicz and Norback, previously applied to blood smears and bone marrow in patients affected by leukaemia, the authors found 8 principal distribution patterns of AgNORs. Recording the percentage of the single patterns in every case it was possible to individualize two quite homogeneous groups. The authors maintain that in this way, avoiding complex numerical evaluations and statistical analysis, it is possible to easily classify the gastric lymphomas. We suggest that an improvement of the results could be achieved by comparing the immunophenotype of the cellular lymphomatous populations, and the AgNORs pattern with patients survival.
采用AgNORs方法对8例原发性胃淋巴瘤进行研究，以确定核仁组织区（NORs）的分布模式。作者修改并举例说明了Nikicicz和Norback先前应用于白血病患者血涂片和骨髓的方案，发现了8种主要的AgNORs分布模式。记录每种情况下单一模式的百分比，就有可能区分出两个相当同质的组。作者认为，通过这种方式，避免复杂的数值评估和统计分析，可以轻松地对胃淋巴瘤进行分类。我们建议，通过比较细胞淋巴瘤群体的免疫表型以及AgNORs模式与患者生存率，可以提高结果的准确性。
