Good W V, Muci-Mendoza R, Berg B O, Frederick D R, Hoyt C S
Department of Ophthalmology, University of California Medical Center, San Francisco 94143.
Aust N Z J Ophthalmol. 1992 Nov;20(4):319-23. doi: 10.1111/j.1442-9071.1992.tb00744.x.
We reviewed the records of 10 children with optic neuritis in whom recovery of vision was poor or incomplete. Our cases were otherwise similar to those described in previous studies in that they were always bilateral, often accompanied by a viral prodrome (seven of 10), and usually associated with disc oedema (seven of 10). Seven of twenty eyes had a final visual acuity of 6/60 or worse and only one patient regained 6/6 vision in either eye. In three patients the best vision in either eye was 6/60 or worse. Recovery of vision was often slow, taking up to six years. Five of 10 patients have developed multiple sclerosis (MS), and one child had acute disseminated encephalomyelitis (ADEM) with optic neuritis. Optic neuritis in children does not always carry a good prognosis for recovery of vision; however, the failure of vision recovery in a short period of time does not necessarily indicate a poor outcome. Some children with optic neuritis develop MS, which can develop even when optic neuritis follows a viral illness.
我们回顾了10例视力恢复不佳或不完全恢复的视神经炎患儿的病历。我们的病例在其他方面与先前研究中描述的病例相似,即总是双侧发病,常伴有病毒前驱症状(10例中有7例),且通常伴有视盘水肿(10例中有7例)。20只眼中有7只最终视力为6/60或更差,只有1例患者一只眼恢复到了6/6的视力。3例患者任何一只眼的最佳视力为6/60或更差。视力恢复通常很缓慢,长达6年。10例患者中有5例已发展为多发性硬化症(MS),1名儿童患有伴有视神经炎的急性播散性脑脊髓炎(ADEM)。儿童视神经炎并不总是预示着视力恢复的良好预后;然而,短期内视力未能恢复并不一定表明预后不良。一些患有视神经炎的儿童会发展为MS,即使视神经炎继发于病毒感染性疾病时也可能发生。