儿童视神经炎的临床特征。
The clinical profile of childhood optic neuritis.
作者信息
Lana-Peixoto M A, Andrade G C
机构信息
Department of Neuro-Ophthalmology, Hospital São Geraldo, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil.
出版信息
Arq Neuropsiquiatr. 2001 Jun;59(2-B):311-7. doi: 10.1590/s0004-282x2001000300001.
PURPOSE
To report the clinical features and outcome of a series of children with optic neuritis.
METHODS
We reviewed the medical records of patients up to 16 years old with optic neuritis. Group 1 comprised children seen up to two weeks after the onset of visual loss; Group 2 comprised patients already harboring optic atrophy.
RESULTS
There were 15 boys and 12 girls. The mean age was 10.9 years. Bilateral optic neuritis occurred in 10. Optic disc pallor was found in 35%, edema in 46%, and 19% had normal fundus. During follow-up visual acuity improved in all but one eye in Group 1, and in six of seven eyes in children in Group 2. Just one child converted to multiple sclerosis.
CONCLUSIONS
This study shows that the clinical features of childhood optic neuritis differ from those observed in adults. In children it has a better visual outcome and a lower conversion rate to multiple sclerosis than in adults.
目的
报告一系列儿童视神经炎的临床特征及转归。
方法
我们回顾了16岁及以下视神经炎患者的病历。第1组包括视力丧失发作后两周内就诊的儿童；第2组包括已患有视神经萎缩的患者。
结果
共有15名男孩和12名女孩。平均年龄为10.9岁。10例为双侧视神经炎。35%的患者视盘苍白，46%有水肿，19%眼底正常。随访期间，第1组除1只眼外其他所有眼睛的视力均有改善，第2组儿童的7只眼中有6只眼视力改善。仅有1名儿童转变为多发性硬化症。
结论
本研究表明儿童视神经炎的临床特征与成人不同。与成人相比，儿童视神经炎的视力转归更好，转变为多发性硬化症的比例更低。
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