原发性肾活检中塌陷性肾小球病与膜性肾小球肾炎共存：3例HIV阴性患者的报告
Collapsing glomerulopathy coexisting with membranous glomerulonephritis in native kidney biopsies: a report of 3 HIV-negative patients.
作者信息
Al-Shamari Ali, Yeung Kit, Levin Adeera, Taylor Paul, Magil Alexander
机构信息
Division of Nephrology, University of British Columbia, Vancouver, BC, Canada.
出版信息
Am J Kidney Dis. 2003 Sep;42(3):591-5. doi: 10.1016/s0272-6386(03)00793-5.
Collapsing glomerulopathy (CG), a variant of idiopathic focal segmental glomerulosclerosis (FSGS), can occur in both human immunodeficiency virus (HIV)-positive and HIV-negative patients. Idiopathic membranous glomerulonephritis (MGN) has been reported to coexist with FSGS, but rarely with CG. We report 3 HIV-negative patients (2 men, 1 woman) who developed nephrotic syndrome secondary to MGN complicated by CG, with relatively rapid disease progression despite aggressive therapy.
塌陷性肾小球病（CG）是特发性局灶节段性肾小球硬化（FSGS）的一种变异型，可发生于人类免疫缺陷病毒（HIV）阳性和HIV阴性患者。据报道，特发性膜性肾小球肾炎（MGN）可与FSGS共存，但很少与CG共存。我们报告了3例HIV阴性患者（2例男性，1例女性），他们继发于MGN合并CG而出现肾病综合征，尽管进行了积极治疗，但疾病进展相对较快。
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