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[慢性应激与低浓度一氧化碳联合暴露下的细胞免疫指标(II)。实验研究]

[Cellular immunity indices in combined chronic exposure to stress and low concentrations of carbon monoxide (II). Experimental research].

作者信息

Dueva L A, Tolmachev D A, Volkova A P

出版信息

Gig Tr Prof Zabol. 1992(8):25-7.

PMID:1295794
Abstract

Studies of the chronic combined effects of carbon monoxide low concentrations and psychoemotional stress revealed changes in the peripheral lymphocyte subpopulation in all groups of examinees, connected with the defense activation of the humoral immunity and functional decrease of T lymphocytes. Analysis of correlations of cell subpopulations revealed disorders of their relationships, augmenting with the intensity of exposure. Combined action of carbon monoxide in the maximal of studies concentrations with stress resulted in the most severe changes of nonspecific immunity, which proves decompensated decrease of immunity.

摘要

对低浓度一氧化碳与心理情绪应激的慢性联合效应的研究表明,所有受试组的外周淋巴细胞亚群均发生了变化,这与体液免疫的防御激活和T淋巴细胞功能下降有关。对细胞亚群相关性的分析揭示了它们之间关系的紊乱,且随着暴露强度的增加而加剧。在研究的最高浓度下,一氧化碳与应激的联合作用导致非特异性免疫发生最严重的变化,这证明了免疫功能的失代偿性下降。

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