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多发性硬化症和帕金森病中的预期协同发音

Anticipatory coarticulation in multiple sclerosis and Parkinson's disease.

作者信息

Tjaden Kris

机构信息

Department of Communicative Disorders and Sciences, University at Buffalo, Buffalo, NY 14214-3005, USA.

出版信息

J Speech Lang Hear Res. 2003 Aug;46(4):990-1008. doi: 10.1044/1092-4388(2003/077).

DOI:10.1044/1092-4388(2003/077)
PMID:12959475
Abstract

Research investigating coarticulatory patterns in dysarthria has the potential to provide insight regarding deficits in the organizational coherence of phonetic events that may underlie deviant perceptual characteristics. The current study investigated anticipatory coarticulation for 17 speakers with multiple sclerosis (MS), 12 speakers with Parkinson's disease (PD), and 29 healthy control speakers. V1-C-V2 sequences were used to investigate intersyllabic vowel to vowel effects (V2 to V1 effects), intersyllabic consonant to vowel effects (C to V1 effects), and intrasyllabic vowel to consonant effects (V2 to C effects). Second formant frequencies and first moment coefficients were used to infer coarticulation. In general, patterns of intersyllabic and intrasyllabic coarticulation were similar for speakers with MS, speakers with PD, and healthy control speakers. It therefore appears unlikely that coarticulatory patterns for speakers diagnosed with MS or PD strongly contribute to deviant perceptual characteristics, at least for the current group of speakers, most of whom were mildly to moderately impaired. Anticipatory vowel effects in /k/+vowel sequences, however, tended to be reduced for speakers with MS and speakers with PD when data for these 2 speaker groups were pooled and compared to control speakers. These results were not attributable to group differences in speech rate or articulatory scaling, defined as the extent of articulatory movements, and further suggest that coarticulatory deficits are not unique to particular neurological diagnoses or dysarthrias. Potential explanations for the /k/+vowel results include difficulties with anterior-posterior tongue positioning and the competing influences of minimizing articulatory effort and maintaining sufficient perceptual contrast. Despite this subtle difference in coarticulation between disordered speakers and healthy control speakers, the overall results suggest that anticipatory coarticulation for speakers with MS and speakers with PD is preserved.

摘要

研究构音障碍中的协同发音模式,有可能为语音事件组织连贯性方面的缺陷提供见解,而这些缺陷可能是异常感知特征的潜在原因。本研究调查了17名多发性硬化症(MS)患者、12名帕金森病(PD)患者和29名健康对照者的预期协同发音。使用V1-C-V2序列来研究音节间元音到元音的影响(V2对V1的影响)、音节间辅音到元音的影响(C对V1的影响)以及音节内元音到辅音的影响(V2对C的影响)。利用第二共振峰频率和第一矩系数来推断协同发音。总体而言,MS患者、PD患者和健康对照者的音节间和音节内协同发音模式相似。因此,至少对于当前这组大多数为轻度至中度受损的患者来说,被诊断为MS或PD的患者的协同发音模式似乎不太可能对异常感知特征有很大影响。然而,当将这两组患者的数据合并并与对照者进行比较时,MS患者和PD患者在/k/+元音序列中的预期元音影响往往会降低。这些结果并非归因于语速或发音缩放(定义为发音动作的程度)方面的组间差异,并且进一步表明协同发音缺陷并非特定神经诊断或构音障碍所特有。对/k/+元音结果的潜在解释包括前后舌位定位困难以及在最小化发音努力和保持足够感知对比度之间的相互竞争影响。尽管无序发音者和健康对照者在协同发音方面存在这种细微差异,但总体结果表明MS患者和PD患者的预期协同发音得以保留。

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