Chai C Y, Hou M F, Huang T J, Lin H J
Department of Pathology, Kaohsiung Medical College, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1992 Oct;8(10):576-80.
The inflammatory fibroid polyp is a rare, polypoid lesion in the gastrointestinal tract. It occurs in the stomach, small intestine, and large intestine in descending order of frequency. This case report shows an ileal inflammatory fibroid polyp that causes ileoileal intussusception. So far, the histogenesis and pathogenesis of these kinds of polyps are still uncertain. Under the microscopic examination, the lesion appears to be made up of spindle-shaped or stellate cells that are morphologically identical to proliferating fibroblasts. Immunostaining results are strongly positive for vimentin and focally positive for S100 protein. However, epithelial membrane antigen, factor VIII R Ag, smooth muscle actin, and lysozyme test are all negative. This favors the view that the inflammatory fibroid polyp is fibroblastic in origin.
炎性纤维瘤性息肉是胃肠道中一种罕见的息肉样病变。它按发生频率由高到低依次出现在胃、小肠和大肠。本病例报告展示了一例导致回肠套叠的回肠炎性纤维瘤性息肉。迄今为止，这类息肉的组织发生和发病机制仍不明确。在显微镜检查下，病变似乎由形态上与增殖的成纤维细胞相同的梭形或星状细胞组成。免疫染色结果显示波形蛋白呈强阳性，S100蛋白呈局灶性阳性。然而，上皮膜抗原、因子VIII R Ag、平滑肌肌动蛋白和溶菌酶检测均为阴性。这支持炎性纤维瘤性息肉起源于成纤维细胞的观点。
