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[溃疡性结肠炎和克罗恩病患者病历的回顾性分析]

[Retrospective analysis of case histories of patients with ulcerative colitis and Crohn's disease].

作者信息

Zvirbliene Aida, Kiudelis Gediminas, Kupcinskas Limas

机构信息

Clinic of Gastroenterology, Kaunas University of Medicine Hospital, 3007 Kaunas, Lithuania.

出版信息

Medicina (Kaunas). 2003;39(8):745-50.

PMID:12960453
Abstract

Consistent patterns of inflammatory bowel diseases (IBD), difficulties of diagnosis Crohn's disease and ulcerative colitis and peculiarities of their treatment have been studied on the basis of retrospective analysis of IBD patient case histories during 1995-2001 in the Department of Gastroenterology of Kaunas University of Medicine Hospital. Ulcerative colitis and Crohn's disease are chronic diseases that influence the quality of life, mortality and number of hospitalizations with their course varying in different countries. The number of cases hospitalized during the five years period was 273; 80% of which was ulcerative colitis, whereas the percentage of Crohn's disease was 20. The number of cases of ulcerative colitis increased every year while that of Crohn's disease started to grow in 2001. IBD is more common among males than females. It was at the expanse of young females that patients with Crohn's disease were statistically significantly younger than those with ulcerative colitis. Proctosigmoiditis (45.9%) and left colitis (27.1%) are common predominants in ulcerative colitis, while ileocolitis (63.6%) predominates in Crohn's disease. Ulcerative colitis correlates with stool frequency and extent of disease. Course of IBD is rather grave and relapses are quite frequent.

摘要

基于对1995 - 2001年考纳斯医科大学医院胃肠病科炎症性肠病(IBD)患者病历的回顾性分析,研究了IBD的一致模式、克罗恩病和溃疡性结肠炎的诊断困难及其治疗特点。溃疡性结肠炎和克罗恩病是影响生活质量、死亡率和住院次数的慢性疾病,其病程在不同国家有所不同。五年期间住院病例数为273例;其中80%为溃疡性结肠炎,而克罗恩病的比例为20%。溃疡性结肠炎病例数逐年增加,而克罗恩病病例数在2001年开始增长。IBD在男性中比女性更常见。在年轻女性中,克罗恩病患者在统计学上明显比溃疡性结肠炎患者年轻。直肠乙状结肠炎(45.9%)和左半结肠炎(27.1%)是溃疡性结肠炎常见的主要类型,而回结肠型(63.6%)在克罗恩病中占主导。溃疡性结肠炎与大便频率和疾病范围相关。IBD病程相当严重,复发频繁。

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