Rohner Dennis, Jaquiéry Claude, Kunz Christoph, Bucher Peter, Maas Holger, Hammer Beat
Craniofacial Center Hirslanden, Aarau, Switzerland.
Plast Reconstr Surg. 2003 Sep;112(3):748-57. doi: 10.1097/01.PRS.0000069709.89719.79.
Between January of 1998 and May of 2002, 25 prefabricated osseous free flaps (23 fibula and two iliac crest flaps) were transferred in 24 patients to repair maxillary (six flaps) or mandibular (eight flaps) defects after tumor resection, severe maxillary (four flaps) or mandibular (one flap) atrophy (Cawood VI), maxillary (one flap) or mandibular (three flaps) defects after gunshot injury, and maxillary (two flaps) defects after traffic accidents. Prefabrication included insertion of dental implants, positioned with a drilling template in a preplanned position, and split-thickness grafting. Drilling template construction was based on the prosthetic planning. The template determined the position of the implants and the site and angulation of osteotomies, if necessary. The mean delay between prefabrication and flap transfer was 6 weeks (range, 4 to 8 weeks). While the flap was harvested, a bar construction with overdentures was mounted onto the implants. The overdentures were used as an occlusal key for exact three-dimensional positioning of the graft within the defect. The bar construction also helped to stabilize the horseshoe shape of the graft. The follow-up period ranged from 2 months to 4 years (mean, 21 months), during which time two total and three partial flap losses occurred. One total loss was due to thrombosis of the flap veins during the delay period, whereas the other total loss was caused by spasm of the peroneal artery. Two partial losses were due to oversegmentation of the flaps with necrosis of the distal fragment, whereas one partial loss was caused by disruption of the vessel from the distal part. Of the 90 implants that were inserted into the prefabricated flaps during the study period, 10 were lost in conjunction with flap failure; of the remaining 80 implants, four were lost during the observation period, for a success rate of 95 percent. Flap prefabrication based on prosthetic planning offers a powerful tool for various reconstructive problems in the maxillofacial area. Although it involves a two-stage procedure, the time for complete rehabilitation is shorter than with conventional procedures.
1998年1月至2002年5月期间,24例患者共移植了25块预制骨游离皮瓣(23块腓骨皮瓣和2块髂嵴皮瓣),用于修复肿瘤切除术后的上颌骨(6块皮瓣)或下颌骨(8块皮瓣)缺损、严重上颌骨(4块皮瓣)或下颌骨(1块皮瓣)萎缩(Cawood VI级)、枪伤后的上颌骨(1块皮瓣)或下颌骨(3块皮瓣)缺损以及交通事故后的上颌骨(2块皮瓣)缺损。预制过程包括植入牙种植体,通过钻孔模板将其放置在预先规划的位置,并进行断层皮片移植。钻孔模板的构建基于修复计划。必要时,该模板可确定种植体的位置以及截骨的部位和角度。预制与皮瓣移植之间的平均间隔时间为6周(范围为4至8周)。在切取皮瓣时,将带有覆盖义齿的杆状结构安装到种植体上。覆盖义齿用作咬合关键,以在缺损内精确三维定位移植骨。杆状结构还有助于稳定移植骨的马蹄形。随访期为2个月至4年(平均21个月),在此期间发生了2例皮瓣完全丢失和3例部分丢失。1例完全丢失是由于延迟期皮瓣静脉血栓形成,而另1例完全丢失是由腓动脉痉挛引起的。2例部分丢失是由于皮瓣过度分割导致远端骨段坏死,而1例部分丢失是由远端血管破裂引起的。在研究期间植入预制皮瓣的90颗种植体中,有10颗因皮瓣失败而丢失;其余80颗种植体中,有4颗在观察期内丢失,成功率为95%。基于修复计划的皮瓣预制为颌面区域的各种重建问题提供了有力工具。虽然它涉及两阶段手术,但完全康复的时间比传统手术短。