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癌症基因治疗的突破

Breakthroughs in cancer gene therapy.

作者信息

Liu Ke

机构信息

Surgery Branch, Center for Cancer Research, National Institutes of Health, 9000 Rockville Pike, Bldg 10, Room 2B08, Bethesda, MD 20892-1502, USA.

出版信息

Semin Oncol Nurs. 2003 Aug;19(3):217-26. doi: 10.1016/s0749-2081(03)00049-4.

DOI:10.1016/s0749-2081(03)00049-4
PMID:12962011
Abstract

OBJECTIVES

To give oncology nurses an overview on the vectors and selected approaches used in the current clinical trials involving gene transfer to cancer patients.

DATA SOURCES

Peer-reviewed scientific papers, review articles, and book chapters.

CONCLUSION

Significant progress has been made in the field of cancer gene therapy. Different phases of clinical protocols derived from new generations of vectors and novel approaches are being tested for use in the treatment of patients with cancer.

IMPLICATIONS FOR NURSING PRACTICE

Oncology nurses need to be familiar with current advances in the field of cancer gene therapy to expand their role as health care professional, patient educator, and advocate for the treatment of patients with cancer.

摘要

目的

为肿瘤护理人员概述当前涉及向癌症患者进行基因转移的临床试验中所使用的载体及选定方法。

数据来源

同行评审的科学论文、综述文章及书籍章节。

结论

癌症基因治疗领域已取得重大进展。源自新一代载体和新方法的不同阶段临床方案正在进行测试,以用于癌症患者的治疗。

对护理实践的启示

肿瘤护理人员需要熟悉癌症基因治疗领域的当前进展,以扩大其作为医疗保健专业人员、患者教育者及癌症患者治疗倡导者的作用。

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Breakthroughs in cancer gene therapy.癌症基因治疗的突破
Semin Oncol Nurs. 2003 Aug;19(3):217-26. doi: 10.1016/s0749-2081(03)00049-4.
2
Gene therapy: current and future implications for oncology nursing practice.基因治疗:对肿瘤护理实践的当前及未来影响
Semin Oncol Nurs. 1997 May;13(2):115-22. doi: 10.1016/s0749-2081(97)80008-3.
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Biological advances for new treatment approaches.新治疗方法的生物学进展。
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Gene therapy of cancer.
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Trends in cancer therapy: role of monoclonal antibodies.癌症治疗的趋势:单克隆抗体的作用
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Models of Care in Geriatric Oncology Nursing.老年肿瘤护理中的照护模式
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The Institute of Medicine report on high-quality cancer care: implications for oncology nursing.医学研究所关于高质量癌症护理的报告:对肿瘤护理的影响。
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Immunotherapy of cancer for the elderly patient: does allogeneic bone marrow transplantation after nonmyeloablative conditioning provide a new option?老年癌症患者的免疫治疗:非清髓性预处理后的异基因骨髓移植能否提供新的选择?
Cancer Immunol Immunother. 2004 Aug;53(8):659-76. doi: 10.1007/s00262-004-0503-2. Epub 2004 Apr 6.