Honda Hidehiko
Department of Neurology, Jikei University School of Medicine.
Nihon Rinsho. 2003 Aug;61(8):1355-60.
In spite of the proven efficacy of the newer immunomodulative pharmacologic treatments for multiple sclerosis, such as steroid pulse therapy for exacerbation and beta-interferon subcutaneous injections for prevention, those treatments have not yet satisfied the criteria for direct management of the disease. Thus, even now, patients with multiple sclerosis still need symptomatic therapy to improve their quality of life and ameliorate the impairments in their activities of daily living due to their various neurologic deficits. This article reviews the management of a wide range of neurologic symptoms of multiple sclerosis, including spasticity, bladder dysfunction, paroxysmal symptoms, and chronic pain.
尽管新型免疫调节药物治疗多发性硬化症已被证实有效,如用于病情加重期的类固醇冲击疗法以及用于预防的β-干扰素皮下注射,但这些治疗尚未满足直接治疗该疾病的标准。因此,即便在当下,多发性硬化症患者仍需要对症治疗,以改善生活质量,并减轻因各种神经功能缺损而导致的日常生活活动障碍。本文综述了多发性硬化症多种神经症状的治疗方法,包括痉挛、膀胱功能障碍、发作性症状和慢性疼痛。