Berdajs Denis, Patonay Lajos, Turina Marko I
Institute of Anatomy, Histology, and Embryology, Laboratory for Applied and Clinical Anatomy, Semmelweis University Budapest, Budapest, Hungary.
Ann Thorac Surg. 2003 Sep;76(3):732-5; discussion 735-6. doi: 10.1016/s0003-4975(03)00660-x.
Our basic aim was to describe the topographic relation between the sinus node artery and the superior posterior border of the interatrial septum with regard to the sinus node dysfunction that follows the superior transseptal approach to the mitral valve.
During our study 50 human hearts without previous pathologic alterations were analyzed. The position of the sinus node and the course of the sinus node artery were investigated. For identification of the origin of the artery, selective coronary angiograms were performed. The course of sinus node artery and its topographic relation to the interatrial septum was identified by the dry dissections of the hearts. Based on histologic and dry dissected specimens the exact position of the sinus node was determined.
We found that the sinus node artery originates from the right coronary artery in 66% of examined cases and from the left coronary artery in 34% of cases. The sinus node artery crosses the superior posterior border of the interatrial septum in 54% of cases.
Our results were compared with clinical studies focusing the incidence of the sinus rhythm disturbance after the superior transseptal approach. The incidence of rhythm disturbance varies from 52% to 60% of cases. Comparing our morphologic and clinical results we can state that the risk for intraoperative damage to the sinus node artery during the superior transseptal approach to the mitral valve is high.
我们的基本目的是描述在经房间隔上入路行二尖瓣手术导致窦房结功能障碍的情况下,窦房结动脉与房间隔上后缘之间的解剖关系。
在我们的研究中,分析了50例无既往病理改变的人体心脏。研究了窦房结的位置和窦房结动脉的走行。为确定动脉的起源,进行了选择性冠状动脉造影。通过心脏的干式解剖确定窦房结动脉的走行及其与房间隔的解剖关系。基于组织学和干式解剖标本确定窦房结的准确位置。
我们发现,在66%的检查病例中,窦房结动脉起源于右冠状动脉,在34%的病例中起源于左冠状动脉。在54%的病例中,窦房结动脉穿过房间隔的上后缘。
我们的结果与关注经房间隔上入路后窦性心律紊乱发生率的临床研究进行了比较。心律紊乱的发生率在52%至60%的病例中有所不同。比较我们的形态学和临床结果可以表明,在经房间隔上入路行二尖瓣手术期间,窦房结动脉术中受损的风险很高。