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通过检测不同内科疾病患者分泌物中中间代谢酶来测定粘膜的渗出率(作者译)

[Rate of transudation of the mucous membranes by testing the enzymes of the intermediary metabolism in the secretion of patients with different internal diseases (author's transl)].

作者信息

Schorn K, Hochstrasser K, Pasemann V

出版信息

Laryngol Rhinol Otol (Stuttg). 1975 Aug;54(8):659-62.

PMID:129637
Abstract

In patients with increased levels of GOT, GPT, CPK, LDH, SP and AP in serum, the activities of these enzymes in nasal mucus are determined. Even in cases with extreme increase of activity in serum, the enzyme-activities in nasal mucus are normal. From this we concluded first, that the enzymes in nasal mucus are specific products of the intermediary metabolism of the mucous membranes and secondly, that the rate of transsudation of serum proteins by the nasal mucous membrane therefore is very low in physiological state.

摘要

在血清中谷草转氨酶(GOT)、谷丙转氨酶(GPT)、肌酸磷酸激酶(CPK)、乳酸脱氢酶(LDH)、淀粉样蛋白P(SP)和碱性磷酸酶(AP)水平升高的患者中,测定了这些酶在鼻黏液中的活性。即使在血清中酶活性极度升高的情况下,鼻黏液中的酶活性仍属正常。由此我们首先得出结论,鼻黏液中的酶是黏膜中间代谢的特定产物;其次,在生理状态下,鼻黏膜对血清蛋白的滤过率非常低。

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