Köllner Volker, Einsle Franziska, Schade Ina, Maulhardt Tobias, Gulielmos Vassilios, Joraschky Peter
Klinik und Poliklinik für Psychotherapie und Psychosomatik, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307 Dresden, Germany.
Z Psychosom Med Psychother. 2003;49(3):262-74. doi: 10.13109/zptm.2003.49.3.262.
This study examines stress factors, resources of coping, psychopathological symptoms and their influence on health-related quality of life (QoL) in patients after heart or lung transplantation.
82 Patients were examined with the questionnaires SF-36 (QoL), HADS-D (anxiety and depression), IES-R and PTSS-10 (post traumatic stress disorder, PTSD) 32.3 (4-86) months after transplantation. Stress factors, resources and diagnostic criteria for PTSD were investigated by structured interview.
In the entire sample, anxiety, depression and QoL were in the range of normal population. A subgroup of 13 patients with a PTSD diagnose had significantly reduced QoL. Anxiety and intrusion explained the 42 % variance of psychosocial score of QOL.
There was a lower influence of depression on the medical score of QoL. Psychological symptoms such as anxiety, depression and PTSD significantly influence QoL after heart or lung transplantation. Patients with a PTSD diagnose had poor QoL. Screening for PTSD should be part of routine evaluation after organ transplantation.
本研究调查心脏或肺移植术后患者的应激因素、应对资源、心理病理症状及其对健康相关生活质量（QoL）的影响。
82例患者在移植后32.3（4 - 86）个月接受了SF - 36（生活质量）、HADS - D（焦虑和抑郁）、IES - R和PTSS - 10（创伤后应激障碍，PTSD）问卷调查。通过结构化访谈调查应激因素、资源及PTSD的诊断标准。
在整个样本中，焦虑、抑郁和生活质量处于正常人群范围内。13例被诊断为PTSD的患者亚组生活质量显著降低。焦虑和闯入症状解释了生活质量心理社会评分42%的变异。
抑郁对生活质量医学评分的影响较小。焦虑、抑郁和PTSD等心理症状显著影响心脏或肺移植后的生活质量。被诊断为PTSD的患者生活质量较差。PTSD筛查应成为器官移植后常规评估的一部分。
