Inci E, Karakullukçu B, Aygün G, Yaşar H, Enver O, Yağiz C
Department of Otolaryngology, Head and Neck Surgery, Istanbul University Cerrahpaşa Medical Faculty, Istanbul, Turkey.
J Int Med Res. 2003 Jul-Aug;31(4):307-11. doi: 10.1177/147323000303100408.
Acute tonsillitis is a common childhood disease, but repeated antibiotic treatment may fail, leading to tonsillectomy. Superficial swab cultures do not sufficiently represent the core bacteria present, but fine-needle aspiration may be a promising diagnostic method. We evaluated 58 patients undergoing tonsillectomy, and took superficial and core swabs, and fine-needle aspirations. Staphylococcus aureus was the most common bacterial pathogen identified, present in 26 out of 50 (52%) positive core cultures, followed by Haemophilus influenza in 13 positive core cultures (26%), and group A beta-haemolytic streptococci in 10 positive core cultures (20%). Fine-needle aspiration detected 33 out of 50 positive core cultures (66%), whereas superficial swab culture detected 18 of 50 (36%); the difference being statistically significant. All pathogens detected by superficial swabs and fine-needle aspiration were detected in core cultures. The sensitivity and specificity of fine-needle aspiration were 66% and 100%, respectively, compared with 36% and 100% for superficial swabs. Fine-needle aspiration is therefore a promising method for detecting core bacteria in patients with recurrent tonsillitis.
急性扁桃体炎是一种常见的儿童疾病，但反复使用抗生素治疗可能无效，最终导致扁桃体切除术。表面拭子培养不能充分代表存在的核心细菌，但细针穿刺抽吸可能是一种有前景的诊断方法。我们评估了58例接受扁桃体切除术的患者，采集了表面和核心拭子以及进行了细针穿刺抽吸。金黄色葡萄球菌是最常见的细菌病原体，在50份阳性核心培养物中有26份（52%）检测到，其次是13份阳性核心培养物（26%）中的流感嗜血杆菌，以及10份阳性核心培养物（20%）中的A组β溶血性链球菌。细针穿刺抽吸在50份阳性核心培养物中检测到33份（66%），而表面拭子培养在50份中检测到18份（36%）；差异具有统计学意义。表面拭子和细针穿刺抽吸检测到的所有病原体在核心培养物中均被检测到。细针穿刺抽吸的敏感性和特异性分别为66%和100%，而表面拭子的敏感性和特异性分别为36%和100%。因此，细针穿刺抽吸是检测复发性扁桃体炎患者核心细菌一种有前景的方法。
